AMOCEAssociation of Metabolic and
Obese Care in Eastern India
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Obesity

The Role of Hormones in Obesity

10 April 2025 AMOCE Editorial

Leptin, ghrelin, insulin and cortisol all influence appetite and fat storage.

Obesity is not simply a matter of willpower. A complex network of hormones regulates hunger, satiety and energy storage.

Key hormones

  • Leptin – signals satiety
  • Ghrelin – the hunger hormone
  • Insulin – promotes fat storage
  • Cortisol – stress-related weight gain

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